With trade terms still unfinalised, stockpiling of medicines and the sourcing of alternative transportation and routes has become a stark reality. Contingency planning for a no-deal Brexit is in motion but efforts need to be stepped up to provide certainty to businesses and the public and ensure that Britain does not lose the benefit of connectivity to the European regulatory network. This article considers the contingency measures being implemented, the challenges faced by the life sciences sector in light of Brexit but notes there are still signs of investment in Scotland in particular - all may not be lost!